Thérèse Coffey has been appointed Health Secretary and Deputy Prime Minister, Downing Street said.
In a tweet, 10 Downing Street said: "The Rt Hon Dr Thérèse Coffey MP Therese Coffey has been appointed Secretary of State for Health and Social Care. She will also be Deputy Prime Minister."
She told awaiting journalists outside Downing Street “I’m very excited thank you”.
Liz Truss began her Cabinet reshuffle with a cull of prominent Rishi Sunak supporters, sending Dominic Raab, Grant Shapps and Steve Barclay to the backbenches swiftly after she became Prime Minister.
Thérèse Coffey has been appointed Health Secretary and Deputy Prime Minister, Downing Street said.
PHIL NOBLE
She removed the senior figures who had backed her rival in the Tory leadership race promptly after heading to her House of Commons office following her first speech in Downing Street on Tuesday.
Mr Raab, who was justice secretary as well as second in command to Boris Johnson, had not expected to continue his run in Government, having described Ms Truss’s tax plans as an “electoral suicide note”.
The MP for Esher and Walton announced he would be supporting the Government from the backbenches.
“Thanks to the brilliant MoJ (Ministry of Justice) team for all their hard work over the last year. Good luck to the new PM and her team,” Mr Raab tweeted.
“I look forward to supporting the Government from the backbenches.”
Mr Shapps also tweeted his own exit as Transport Secretary but did not make the same remarks of support for the new Tory leader.
“It has been a privilege to serve as Transport Secretary; a job I loved,” he said.
“Now I look forward to being a strong, independent voice on the backbenches, developing policies that will further the Conservative cause and the interests of my constituents in Welwyn Hatfield.”